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diagnosis algorithm causes hepatology pediatrics management transaminitis classification blood criticalcare elevated hematology hepatitis kidney lactate nephrology overview product reactions seizures
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... Hepatopathy • Acute ... injury) • Ischemic ... #Differential #
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... necrosis (causes: sepsis ... , meds, contrast ... #Kidney #Injury
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Parenchyma • Infectious ... Hepatitis, TPN • Infectious ... : Sepsis, Viral ... #Injury #Differential
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... 10-20x normal - Infection ... #LFTs #transaminitis ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... Transaminitis #LFTs
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Infancy (SUDI) - Differential ... Pneumonia • Sepsis ... Injury: • Deliberate ... Accidental* Other: • Acute ... Algorithm #Causes #Peds
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Mixed - Check Acute ... injury < 26 weeks ... chemistry #diagnosis #differential ... transaminitis #LFTs
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm Maternal Related: • Drugs (Ex. SSRI) •
Lethargic Newborn - Differential ... Congenital: • Birth Injury ... Malformation • TORCH Infection ... Aspiration • Sepsis ... Algorithm #Causes #Peds
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Liver Injury: ... • Infectious: HAV ... #differential #
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm Hepatobiliary: • Acute Hepatitis • Acute
Systemic Causes - Differential ... : • Infectious ... Systemic - Other: • Sepsis ... Emesis #Vomiting #Differential ... Algorithm #Causes #Peds
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