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diagnosis sepsis anesthesia anesthesiology apml differentiation encephalopathy erythematosus intraoperative lactate lupus map neurology oncology posterior pres reversible rheumatology shock sirs
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... vs non-infectious ... circulatory failure o Hypotension ... >2 mmol/L Management ... control (drain abscesses
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
(hypotension persisting ... ≥ 4mmol.l-1 if infection ... Discuss ongoing management ... Intraoperative #Checklist ... #Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... transplantation, Hypertension ... Reversible course Differential ... Diagnosis: • Infection ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... Frank nephritis (hypertension ... , APLA, PAC • Aseptic
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