10 results
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
high risk): o Altered ... Septic Shock • ... /L Management ... control (drain abscesses ... #sirs #shock #lactate
Altered Mental Status - Differential Diagnosis
 • Neurologic: Stroke, Cerebral hypoxia, Cerebral hemorrhage, Seizure, Trauma, TBI,
Altered Mental Status ... - Differential ... Diagnosis • Neurologic ... UTI, Pneumonia, Sepsis ... Encephalitis, Abscess
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... malperfusion - Lactate ... Distributive: Sepsis ... Insufficiency, Liver ... algorithm #treatment #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... glucose by the liver ... /hypoxemia/Sepsis ... assessment - assess ... Acidosis #Elevation #Differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Cardiogenic & Septic Shock ... Localized soft-tissue infection ... Clearance: Systemic liver ... Malaria, Late Sepsis
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia

Severe sepsis (hypotension persisting after initial fluid challenge of
≥ 4mmol.l-1 if infection ... cause) or septic shock ... central and arterial access ... Discuss ongoing management ... Checklist #Diagnosis #Management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Inflammatory: infectious ... (sepsis) or not ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Inflammatory: infectious ... (sepsis) or not ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... /Sepsis/Shock, Autoimmune ... Reversible course Differential ... Syndrome #diagnosis #management ... #neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Mississippi and Ohio River ... by culture or serology ... Sinusitis • Brain abscess ... fever • Septic shock ... Fungal #Diagnosis #Management