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diagnosis causes criticalcare classification acidosis algorithm lactic overview sepsis activation acute anesthesia anesthesiology checklist elevation encephalopathy hematology hepatology injury intraoperative
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... high risk): o Altered ... /L Management ... control (drain abscesses ... #sirs #shock #lactate
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... Distributive: Sepsis ... Insufficiency, Liver ... Abdominal compartment syndrome ... algorithm #treatment #management
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Cardiogenic & Septic Shock ... Ischemia, Compartment Syndrome ... Clearance: Systemic liver ... Malaria, Late Sepsis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... /hypoxemia/Sepsis ... assessment - assess ... - Compartment syndrome ... Acidosis #Elevation #Differential
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Parenchyma • Infectious ... obstruction, HELLP Syndrome ... Hepatic Artery: Shock ... : Sepsis, Viral
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
≥ 4mmol.l-1 if infection ... cause) or septic shock ... central and arterial access ... Discuss ongoing management ... Checklist #Diagnosis #Management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Inflammatory: infectious ... (sepsis) or not ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Inflammatory: infectious ... (sepsis) or not ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Preeclampsia, Eclampsia, Infection ... /Sepsis/Shock, Autoimmune ... Reversible course Differential ... Diagnosis: • Infection ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... brucellosis) • Sepsis ... thrombocytopenia • Liver ... Triglycerides • ↑ Lactate ... #Diagnosis #Management
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