18 results
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... - Acute Bleeding ... Avoid meds that ... though safety assessment ... #treatment #hematology
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
Initial assessment ... NAFLD fibrosis score ... with values <1.3 ... algorithm #Referral #Management ... #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
>1.5, and both values ... (Wilson disease ... Uncertain alcohol use assessment ... ., AST or >400 IU ... Hepatitis #AH #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... immunosuppression • Acute ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Factors: • SICU ... > MICU, ♀, ↑Age ... → Calculate 4T score ... • If 4T score ... #Treatment #Hematology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
>1.5, and both values ... (Wilson disease ... Uncertain alcohol use assessment ... ., AST or >400 IU ... Hepatitis #Diagnosis #Hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
+ Etiological Assessment ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology