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treatment apml differentiation hemophagocytic hemophilia heparin hit hlh induced leukostasis lymphohistiocytosis lysis oncology thrombocytopenia tls tumor
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Factors: • SICU ... > MICU, ♀, ↑Age ... → Calculate 4T score ... • If 4T score ... #Hematology #HemeOnc
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Rare: DAH, acute ... organ dysfuxtion, ICU ... Differentiation #Syndrome ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... #TLS #diagnosis ... #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... severity Treatment - Acute ... Avoid meds that ... though safety assessment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... : HScore a. ... #Management #Hematology ... #HemeOnc
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