18 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... symptoms of liver disease ... Calculate R-Value ... gastroenterology #hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... → Calculate 4T score ... • If 4T score ... #HIT #Heparin #Induced ... #Treatment #Hematology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
>1.5, and both values ... (Wilson disease ... Possible drug-induced ... Uncertain alcohol use assessment ... Hepatitis #AH #hepatology
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
Initial assessment ... NAFLD fibrosis score ... with values <1.3 ... algorithm #Referral #Management ... #Hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
>1.5, and both values ... Possible drug-induced ... Uncertain alcohol use assessment ... ., AST or >400 IU ... Hepatitis #Diagnosis #Hepatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... • Shear stress-induced ... Syndrome #Diagnosis #Management ... #treatment #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... primarily on clinical assessment ... and to adjust treatment ... #Hematology #HIT ... #Heparin #Induced
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... Avoid meds that ... though safety assessment ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
+ Etiological Assessment ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology