13 results
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Hypophosphatemia ... depletion: Respiratory alkalosis ... ), Hungry bone syndrome ... • Renal losses ... Algorithm #causes #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Glucose, Acute resp. alkalosis ... , Hungry bone syndrome ... FEPO4 ≥ 5% - Renal ... Workup #phosphate #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... Medications Renal ... Losses Non-renal ... #low #potassium
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... 8.0 mg/dL • Potassium ... Intravenous fluids • Renal ... Rasburicase • Hyperphosphatemia ... #TumorLysis #Syndrome
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic Alkalosis ... diuretics after renal ... generally indicates a renal ... other • Severe potassium ... Diagnosis #Causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... suggests extra-renal ... - Metabolic Alkalosis ... #differential #potassium ... #nephrology #low
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
steatorrhea) • Renal ... osmotic diuresis, Potassium ... depletion, Familial hypophosphatemia ... Tubulointerstitial renal ... differential #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Monitor potassium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Hyperkalemia • Hyperphosphatemia ... or compartment syndrome ... Monitor potassium ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Hypokalemia (renal ... potassium wasting ... , Renal tubular ... Rhabdomyolysis Treatment ... #management #pathophysiology