19 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Alzheimer's (99% of cases ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Causes of Hemiplegia ... • Apraxia • ... Acalculia • Alexia ... Cognition/Confusion, Dementia ... Diagnosis #Algorithm #Causes
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stabilizers: Mechanism and ... Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Vitamin D - Bone disease ... • Thiamine - Nausea ... dysfunction, gait ataxia ... sensory neuropathy, ataxia ... Calcium - Bone disease
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Krabbe Disease ... this interesting case ... of Krabbe disease ... confirmatory lab testing and ... failure, cerebellar ataxia
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... of Vitamin B12 and ... effects including ataxia ... use of N2O can cause ... #Pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... electrolyte losses - Ataxia ... Hyperventilation, Dizziness, Nausea ... muscle function, Ataxia ... differential #diagnosis #causes
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Demyelinating disease ... caused by the JC ... monoparesis), limb ataxia ... , gait ataxia, and ... opportunistic #InfectiousDiseases
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Neurocognitive Disorder (HAND ... impairment • HIV dementia ... Pathophysiology ... ataxia ... neurocognitive #disorder #dementia
Causes of Dysarthria - Differential Diagnosis Algorithm
Lower Motor Neuron - Slow, Low Volume, Breathy Speech, Tongue
Causes of Dysarthria ... • Motor Neuron Disease ... Lateral Sclerosis Ataxic ... Spinal-Cerebellar Ataxia ... • Parkinson's Disease