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encephalopathy neurology thiamine differential wernicke nutrition oncology anemia aplastic apml criteria defects differentiation immune inflammatory inherited iris korsakoff platelet reconstitution
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... of confusion, ataxia ... (broad-based gait ... #vitaminB1 #B1 # ... #diagnosis #comparison
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
Management Diagnosis ... dysfunction (e.g. gait ... ataxia - usually ... (chronic B1 deficiency ... #Diagnosis #Management
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency Clinical Diagnosis - Caine Criteria (2 out of 4):
Acute Thiamine (B1 ... Diagnosis - Caine ... dysfunction and gait ... ataxia is only ... #Deficiency #diagnosis
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... Haemolytic anaemia, ataxia ... • Thiamine B1 ... Wernicke-Korsakoff syndrome ... #differential #diagnosis
Wernicke Encephalopathy - Triad Encephalopathy • Disorientation • Indifference • Inattentiveness Ocular motor dysfunction
gaze palsies Ataxia ... • Gait • ... Encephalopathy #Syndrome ... #Triad #Diagnosis ... Neurology #Thiamine #Deficiency
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... a storage pool deficiency ... Platelet #Defects #comparison ... #differential #diagnosis ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... anemia, GATA2 deficiency ... , CTLA4 deficiency ... Anemia #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... effusions, weight gain ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... blindness, or gait ... ataxia • Papillomavirus ... #Inflammatory #Syndrome ... #Management
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