22 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Thiamine (B1) Deficiency ... dysfunction - Dietary deficiency ... dysfunction and gait ... ataxia is only ... #Thiamine #B1 #Deficiency
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
B1 (Thiamine) Deficiency ... Diagnosis and Management ... dysfunction (e.g. gait ... ataxia - usually ... #Diagnosis #Management
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Syndrome - Thiamine Deficiency ... thiamine (vitamin B1) deficiency ... of confusion, ataxia ... (broad-based gait ... #B1 #thiamine #deficiency
Causes of Gait Disturbance - Differential Diagnosis Algorithm
Sporadic
 • Vascular
 • Infection
 • Toxic
 • Nutrition
Causes of Gait Disturbance ... • Friedrich's Ataxia ... Childhood Catalytic Deficiency ... Childhood Catalytic Deficiency ... Niemann-Pick Disease #Gait
Wernicke Encephalopathy - Triad

Encephalopathy 
 • Disorientation 
 • Indifference 
 • Inattentiveness 
Ocular motor dysfunction
gaze palsies Ataxia ... • Gait • ... Neurology #Thiamine #Deficiency
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
severe, ADAMTS13 deficiency ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
hypothyroidism • Zinc deficiency ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... ) - Waddling gait ... Hyophosphatasia #hepatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
mevalonate kinase deficiency ... Disease #diagnosis #management ... #treatment #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... slow - do not wait ... Management: • ... diagnosis and management ... #Treatment #Hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... parasthesias, gait ... B12 #Cobalamin #Deficiency ... #diagnosis #management