13 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Deafness Signs ... slowness, Psychosis/dementia ... , Ataxia, Poverty ... Carpal timel syndrome
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
of Hemiplegia - Differential ... Acalculia • Alexia ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... Hemiplegia #Neurology #Differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Aphaso-apraxo-agnosia syndrome ... atrophy Lewy body dementia ... (parkinsonian signs ... Frontotemporal dementia ... #Differential #
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Haemolytic anaemia, ataxia ... Wernicke-Korsakoff syndrome ... Vitamins #Deficiency #differential ... #diagnosis #signs
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... CNS: Tremors, Ataxia ... #diagnosis #pathophysiology ... #symptoms #signs
Pulmonary Pathology and Associated Lung Ultrasound Findings
Pneumothorax:
 - No lung sliding/barcode sign
 - Lung point (hard
sliding/barcode sign ... Respiratory Distress Syndrome ... submassive PE) POCUS ... #pulmonary #differential ... #Lung #POCUS #ultrasound
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... - Refeeding syndrome ... Ophthalmoplegia - Ataxia ... Manifestations #Differential ... beriberi #nutrition #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... → Syncope • Signs ... electrolyte losses - Ataxia ... muscle function, Ataxia
Signs and Symptoms Associated With Different Headache Etiologies
 • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... vasoconstriction syndrome ... vasoconstriction syndrome ... #headache #signs ... symptoms #clues #differential