10 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... not required in all ... or if a primary hematologic ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... incidentally during medical ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... complete paralysis of all ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Treatment:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... non-essential drug/HDS treatments ... for alternative causes ... Hepatic vascular disorder ... (e.g. ascites),
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... trolley, anaphylaxis treatment ... pack. ❸ Remove all ... require prolonged treatment ... alternate vasopressor (e.g
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... the most common cause ... hypertension and/or drug treatment ... , eg, cyclic neutropenia ... #hematology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... complete paralysis of all ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... • Thrombosis (e.g ... ET-associated mutation (e.g ... hemoproliferative disorder ... thrombocytosis (e.g