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diagnosis differential management arterial cancer differentiation embolism emergencies leukemia lysis oncologic thrombosis tls vascular venous
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... Pathophysiology: ... high WBC count cause ... limb ischemia, bowel ... #management #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Leukostasis: • ... paradoxus • Beck triad ... EMERGENCIES: Tumor
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... treatment Pathophysiology ... #management #hematology ... #oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... fibrillation ... coagulation and other causes ... #pathophysiology ... #hematology #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ↑ Can develop leukostasis ... Fibrinolysis & DIC • Tumor ... #Leukemia #Hematology ... #Oncology #Diagnosis
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