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hematology diagnosis microscopy rbc blood clinical morphology smear atlas differential path bloodsmear key pathology acanthocytes algorithm anemia bite blister bloodcell
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 1. Old samples
Autoagglutination ... Schistocytes #Pyknocytes #Elliptocytes
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
Elliptocyte - ... elliptocytosis, elliptocytes ... #Blood #Smear #Elliptocyte
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... Autoagglutination ... Microscopy #RBC #Autoagglutination
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... Autoagglutination ... Microscopy #RBC #Autoagglutination
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Bite cell, Elliptocyte
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myeloproliferative anemia • Elliptocytes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
pyropoikilocytes, elliptocytes
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Oxidative drugs Elliptocyte
Morphologic Findings in Red Blood Cells Basophilic stippling - Small blue dots in red cells, due to
cell membrane Elliptocytes
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
Autoagglutination
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