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Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Monitor & correct B12 ... (B12, MMA) for ... symptoms even if wnl B12 ... fatigue despite disease
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... intrinsic factor, IF) Clinical ... to IBD, celiac disease ... who don't take B12
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
super-antigen mediated disease ... Transverse Myelitis - Clinical ... Check Vitamin B12 ... MCTD - Bechet disease ... Deficiency: - Vitamin B12
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Neuropathy ALP is critical ... Malnutrition • Wilson's disease ... Pernicious anemia/B12
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin B12 ... : SIBO, Celiac disease ... pylori infection, B12 ... BrighamChiefs #Vitamin #B12
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... • Thiamine B1 ... • Riboflavin B2 ... gestation • Vitamin B12
Demyelinating Diseases - Differential Diagnosis • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE •
Demyelinating Diseases ... Other: Vitamin B12 ... Demyelinating #Diseases
Dizziness - Differential Diagnosis Framework "Tell me what you mean by dizzy without using the word dizzy." Vertigo:
Neuritis, Meniere's Disease ... Cardiac: Valvular Disease ... neuropathy (DM, B12 ... Dysfunction: Parkinson's disease ... Coordination/Strength: B12
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic disease ... Macrocytic RBC: Vitamin B12 ... deficiency, Liver Disease ... Uremia, Liver disease ... Hemoglobin SS disease
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