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Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... #Clinical #Path ... #BloodSmear #Blood
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... , Thalassemia Basophilic ... #Peripheral #Blood ... interpretation #clinical ... #anemia
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
another peripheral blood ... iron deficiency anemia ... #Clinical #Path ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood ... fetus/newborn the causes ... proerythroblast – basophilic ... #Clinical #Path ... #Peds #BloodSmear
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Deficiency (Eg Causes ... : Chronic Blood ... TlBC > 18% • Anemia ... MCV/RBC<13, +/- basophilic
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• stored red blood ... • chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Differential #Causes
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
inclusions in the red blood ... the peripheral blood ... /megaloblastic anaemia ... #Clinical #Pathology ... #Microscopy #BloodSmear
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... seen in hemolytic anemias ... Clinical conditions ... #Clinical #Path ... #BloodSmear #Blood