17 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... smear Immune-mediated ... Anemias (AIHAs) ... Anemias (AHAs)
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia ... anemia (e.g. ... anemia Sickled ... , Thalassemia Basophilic ... #anemia
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... bilirubin LDH Peripheral ... smear Haptoglobin ... #Anemia #Laboratory ... #Testing #workup
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
anemia. ... DIC is a clinical ... anemia is characterized ... #anemia #Hematology ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... blood smear + DAT ... → Sickle Cell anemia ... anemia (TTP, HUS ... #Anemia #Differential
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... smear, a reticulocyte ... elevated, but anemia ... megaloblastic anemia ... #Macrocytic #Anemia
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
Here is another peripheral ... blood smear demonstrating ... iron deficiency anemia ... #Clinical #Path ... #BloodSmear #Anemia
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... with spur-cell anemia ... anemia that can ... Spur-cell anemia ... #NEJM #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... thalassemia, S Lepore • Basophilic ... #Anemia #Differential ... #workup #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... for degree of anemia ... thecurbsiders podcast #Anemia ... #Workup #Hematology