11 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... purpura: strong sign ... Lab Tests: • CBC
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... • Ulcerated, erythematous ... Differential Diagnosis ... • Goodpasture syndrome ... #rash #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... titers > 1:80 • CBC ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... association • M > F Clinical ... vessel vasculitis ... (Clinical Dx). ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... ischemia • Skin: Erythematous ... • Cogan syndrome
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Leukocytoclastic vasculitis ... Leukemia cutis Diagnosis ... - CBC may also ... #diagnosis #dermatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Paraneoplastic effects of SCC ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs ... Coarctation of aorta, Vasculitis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... nose, ears, or fingers ... hemolytic #anemia #hematology