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syndrome differential hematology management caudaequina causes chronic cll differentiation equina immune inflammatory iris leukemia lymphocytic neurology reconstitution workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... : >3 symptoms, or ... fluid overload, PCC ... #hematology #oncology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Differential Diagnosis ... distinguishing feature ... axial T1 and T2 Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphocytosis on CBC ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
exaggerated inflammatory features ... onset of illness features ... leukoencephalopathy (PML ... Confusion, visual symptoms ... Calmette-Guérin (BCG
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