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diagnosis hepatology differential liver management causes aclf aih alcoholic autoimmune cirrhosis dili druginduced encephalopathy fatigue gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Infections Alcohol-Associated ... Drug-Induced Liver Injury
Causes of Encephalopathy - Differential Diagnosis Algorithm Hyperacute: - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
Differential Diagnosis Algorithm ... encephalopathy Acute ... Inflammatory (Acute ... conditions: Heart failure ... neurocognitive disease
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... • Malignancy Infectious ... Epstein-Barr Virus • Hepatitis ... Pulmonary Disease ... Neurologic •
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... Alcohol-related liver disease ... dechallenge • Acute
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Infectious: HAV ... > 2 • NASH, Chronic ... > 3 • Chronic
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... failure ... - Symptoms of chronic ... pattern of liver injury
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Screen for infection ... injury with serum ... - Concomitant diseases ... - Multiorgan failure
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