27 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure (ACLF) Clinical ... months without treatment ... underlying liver disease ... Drug-Induced Liver Injury
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Disorders: • Chronic ... associated with the BCR-ABL1 ... translocation • Acute ... Colitis and Crohn’s Disease ... #hematology #basophils
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... Hepatocellular: Viral infections ... Alcohol-related liver disease ... dechallenge • Acute
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... • Infectious: HAV ... > 3 • Chronic ... diagnosis #algorithm #hepatology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Fever Hematologic disease ... caused by Bartonella ... Lutzomyia verrucarum Clinical ... toxo reactivation Clinical ... TREATMENT: ​• Acute
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
presents with acute ... 85% • < 50% in chronic ... to 12 weeks for acute ... has five major clinical ... fungal stain of clinical
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Statins - ETOH - Infection ... Dermatomyositis Clinical ... disease 2. ... #treatment #nephrology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... extramedullary disease ... Philadelphia - BCR-ABL ... -> AML: Blast crises ... #Leukemia #Hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
trypanosomiasis) is an infectious ... disease caused ... family Route of infections ... weeks incubation Acute ... Tests - check Acute