8 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Failure Infections Alcohol-Associated ... Drug-Induced Liver Injury ... gastroenterology #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... HSV • Toxic: Alcohol ... #Differential #Diagnosis ... #algorithm #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... concentrations in: RBCs ... : • Early acute ... hepatitisAcute ... fever) • Drugs (alcohol
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular ... ALT Ratios: • Alcoholic ... muscle, kidneys • LDH ... #diagnosis #algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... and Differential Diagnosis ... cryoglobulins, hepatitis ... fragmentocytes, LDH
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure (ALF ... ALT Ratios: • Alcoholic ... liver disease: ... muscle, Kidneys • LDH ... liver #chemistry #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... dechallenge • Acute ... #Diagnosis #Algorithm
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... injury with serum ... - Concomitant diseases