15 results
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm

 • Chronic Myocardial Injury: End
Non-ACS Myocardial ... Injury - Elevated ... End Stage Renal Disease ... Structural Heart Disease ... Distribution: Acute
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... • Legionnaires disease ... : • Early acute ... hepatitisAcute ... Hepatocellular Injury
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... specificity to elevated ... Chronic viral hepatitis ... #hepatitis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... specificity to elevated ... of cholestatic disease ... Alcoholic liver disease
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... Minimal change disease ... malignancies Treatment ... Classification #Nephrology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... pattern of liver injury ... IgG typically elevated ... regarding need for treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... Alcohol-related liver disease ... dechallenge • Acute ... ascites), Chronic hepatitis ... • Autoimmune hepatitis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
(Mannitol) • Elevated ... intraocular pressure • Elevated ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... syndrome, ADEM, Acute ... CSF: Modestly elevated ... An elevated white