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diagnosis hepatology liver algorithm management aclf aki alcoholic cancer chemistry chronic classification dehydrogenase druginduced elevated failure gastroenterology interpretation laboratory lactate
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Circulation Failure Kidney ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... • Iatrogenic: DILI ... : < 1 • Cirrhosis ... #hepatitis #differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... dechallenge • Acute ... • Autoimmune hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... of cholestatic disease ... Alcoholic liver disease ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... LC deposition disease ... malignancies Treatment ... #Kidney #Injury ... Cancer #Oncology #Differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... concentrations in: RBCs ... muscle, liver, and kidney ... : • Early acute ... hepatitis • Acute
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... : - Acute kidney ... injury with serum ... - Concomitant diseases ... HCV, DILI, HCC,
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