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diagnosis differential management chronic hepatology oncology rheumatology @dharsaty acidosis aclf algorithm arthritis causes cirrhosis classification eas elevation encephalopathy fructosamine gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... months without treatment ... underlying liver disease ... Circulation Failure ... Kidney Failure
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Disease Acute ... Supportive with treatment ... hepatomegaly and anemia ... liver failure ... Hepatobiliary #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic kidney ... disease, Hypothyroidism ... • Bone marrow failure ... Index > 3: • Acute ... #diagnosis #calculation
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... • Bone marrow failure ... ’s lymphoma or acute ... #oncology #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... management #phenotypes #workup ... #treatment #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... oxygen sensing (at kidneys ... can drive this disease ... As with many disease ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Bone Marrow Failure ... Myeloproliferative Disease ... Workup: • Complete ... Syndromes #diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... agents, Renal failure ... syndrome, ADEM, Acute ... epilepticus Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... the critically ill ... cardiac output - Acute ... peritonitis - Acute ... 30mmHg) - Severe anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for All ... the presence of anemia ... Screening Tests for Acute ... Arthritis #laboratory #workup
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