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diagnosis chronic differential hepatology management aclf algorithm cirrhosis cll gastroenterology hepatorenal hrs igg4 index leukemia liver lymphocytic nephrology oncology phenotypes
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Circulation Failure ... Kidney Failure
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic kidney ... disease, Hypothyroidism ... • Bone marrow failure ... Index > 3: • Acute ... #diagnosis #calculation
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... management #phenotypes #workup ... #treatment #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... oxygen sensing (at kidneys ... can drive this disease ... As with many disease ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... • Bone marrow failure ... ’s lymphoma or acute ... #oncology #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... hepatitis, or acute ... liver failure ... Treatment Overview ... #Nephrology #Diagnosis
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