11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... Kidney Failure ... #Chronic #Liver
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
, chronic kidney ... , chronic kidney ... , and chronic kidney ... , chronic kidney ... Tolvaptan) • Treatment
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... injury: > 3 • Chronic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... disease, Hepatic ... dechallenge • Acute ... or chronic atypical
Chronic Kidney Disease (CKD):

Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Chronic Kidney Disease ... Treatments that ... and heart failure ... for people with acute ... #CKD #eGFR #Kidney
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... failure ... - Symptoms of chronic ... regarding need for treatment
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Fluid Testing: • WBCs ... Decrease dosage in CKD ... attack + stage ≥3 CKD ... • Oral drug failure ... #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... tubule of the kidney ... thigh bones -> chronic ... Malnutrition • Wilson's disease ... • Neurologic:
Pulmonary Histoplasmosis
Quick Facts on Histoplasma capsulatum:
 • Dimorphic fungi, in yeast phase within the body
 •
valleys • Lives ... , PCR Treatment ... Duration depends on acute ... or chronic disease ... for respiratory failure
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... hepatitis, or acute ... liver failure ... Treatment Overview ... #Nephrology #Diagnosis