14 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Kidney Failure ... #Chronic #Liver
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... kidney disease, ... kidney disease, ... kidney disease ... kidney disease
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... of cholestatic disease ... Alcoholic liver disease ... > 2 • NASH, Chronic ... injury: > 3 • Chronic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... dechallenge • Acute ... hepatitis fibrosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... failure ... - Symptoms of chronic ... regarding need for treatment
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... coccobacillus within the RBCs ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... : - Acute kidney ... - Concomitant diseases ... - Multiorgan failure ... #hepatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... #diagnosis #management ... #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... Fluid Testing: • WBCs ... • Oral drug failure ... Gout #diagnosis #management ... #treatment #rheumatology
Pulmonary Histoplasmosis
Quick Facts on Histoplasma capsulatum:
 • Dimorphic fungi, in yeast phase within the body
 •
, PCR Treatment ... Duration depends on acute ... or chronic disease ... for respiratory failure ... capsulatum #diagnosis #management