15 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... Kidney Failure ... Injury (DILI) ... #Chronic #Liver
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... Dehydration • Heart failure ... cardiorenal syndrome) • Liver ... failure (a.k.a. ... #Kidney #Injury
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... • NASH, Chronic ... > 3 • Chronic
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... > 3 • Chronic
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
, chronic kidney ... , chronic kidney ... , and chronic kidney ... , chronic kidney ... Tolvaptan) • Treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... disease, Hepatic ... dechallenge • Acute ... #Algorithm #hepatology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... • Hematologic ... malignancies Treatment ... #Kidney #Injury
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... failure ... - Symptoms of chronic ... injury, though
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... tubule of the kidney ... thigh bones -> chronic ... Malnutrition • Wilson's disease ... • Neurologic:
Pulmonary Histoplasmosis
Quick Facts on Histoplasma capsulatum:
 • Dimorphic fungi, in yeast phase within the body
 •
valleys • Lives ... , PCR Treatment ... Duration depends on acute ... or chronic disease ... for respiratory failure