14 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... When the specific allergen ... - Red blood cell ... with mismatched blood ... Hypersensitivity #Types #Classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... leading to an allergic ... cell surfaces causes ... causes development ... #Types #Classification
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... Differential #diagnosis #hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... reactions #types #allergy ... #table #classification
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Non-lmmune #Anemia #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Allergic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Allergic reaction ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... The most common causes ... removal from the blood ... / hypoxemia -> focus ... #typea #typeb #classification