11 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... hours - Examples: Anaphylaxis ... lgM antibodies bind ... reactions #types #allergy
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... arrest where other causes ... as a possible cause ... trigger agents (allergy ... Checklist #Diagnosis #Management
Manifestations of Anaphylaxis by Body System

Dermatologic/mucosal

 - Eyes: periorbital swelling/erythema, injected conjunctiva, tears

 - Oral mucosa:
Manifestations of Anaphylaxis ... Body System Dermatologic ... Gastrointestinal - Nausea ... play #Diagnosis #Allergy ... Signs #Symptoms #Anaphylaxis
Antibiotics for severe community-onset pneumonia 

Atypical coverage always 

- Usually azithromycin 500 mg daily 

- Doxycycline
anaphylactic penicillin allergy ... of penicillin anaphylaxis ... only in selected cases ... Antibiotics #Coverage #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... transfusion • Allergic ... reaction / anaphylaxis ... #Differential #Causes ... Checklist #Diagnosis #Management
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Dangerous secondary causes ... : • Anaphylaxis ... pass = Primary Causes ... Differential #Diagnosis #hematology ... #allergy
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... #management #medications ... treatment #diagnosis #causes ... Allergy. 2018;73 ... J Allergy Clin Immunol
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Allergic reaction ... Causes purpura & ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Allergic ... Causes purpura & ... TRALI): Leading cause ... Transfusions #diagnosis #management ... #hematology #reactions
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... eosinophilia Secondary Causes ... : - Allergic disorders ... eosinophilia #diagnosis #hematology ... #differential #management