39 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... cell surfaces causes ... causes development ... An allergic reaction ... #Allergic #Reactions
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
: - Drug reaction ... infection - Allergic ... reaction - Atopic ... + T cells) - Allergic ... hypereosinophilia #HE #Differential
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... released during an allergic ... reaction or asthma ... #Diagnosis #causes ... #hematology #basophils
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
exposure • Non-allergic ... drug reaction - ... cell-mediated in > 90% of cases ... Diagnosis #Treatment #management ... #allergy
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #types #allergy
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... hypersensitivity reaction ... associated with allergic ... (in this case Tegretol ... Images #Clinical #Dermatology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... hypersensitivity reaction ... associated with allergic ... (in this case Tegretol ... Images #Clinical #Dermatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash - Differential ... Bullous impetigo - Reaction ... Vesiculobullous #SkinRash #dermatology ... #Differential # ... Diagnosis #Algorithm #causes
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew ... Thrombocytosis #Platelets #Differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... are asthma, allergy ... , drug reaction, ... Disorders #Algorithm #Differential ... #diagnosis #hematology