16 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... cell-mediated in > 90% of cases ... #Classification ... #Types #Diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... lgE antibodies bind ... When the specific allergen ... #Classification ... Pathophysiology #Allergy
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... of lgE Abs that bind ... cell surfaces causes ... causes development ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #allergy #table ... #classification
There are 2 Major Types of Angioedema:
 - Mast cell / histamine mediated – usually presents
There are 2 Major Types ... AND allergic symptoms ... presents WITHOUT allergic ... #Classification ... #Types #Bradykinin
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... disease, hereditary angioedema ... glomerulonephritis, type ... 1 (50%-80%), type ... #differential #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... activity that bind ... #classification ... #rheumatology #
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Anaphylaxis • Angioedema ... pass = Primary Causes ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology ... #allergy
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
Causes of Pseudocellulitis ... antibiotics and avoid allergic ... Inflammatory Causes ... dermatitis • Angioedema ... #dermatology #skin
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... multifactorial mechanisms Hematologic ... #Differential #Causes