34 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... Understand vasoactive drug ... pharmacology ... shock #Vasoactive #Drugs ... #pharmacology #
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
Drugs with good ... Drugs with moderate ... Drugs with low CNS ... Drugs of no use ... Perfusion #CSF #Pharmacology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Sedative-Hypnotic Drugs ... Benzodiazepines: - Bind ... Barbituates: - Bind ... Hyponotics: - Bind ... #medications #pharmacology
Neonatal Resuscitation – Circulation and Drugs
Consider drugs (k) if heart rate beats/min in spite of adequate
Circulation and Drugs ... Consider drugs ... Drugs should be ... umbilical venous catheter ... #Medications #Pharmacology
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
cephalosporins bind ... that PCN does not bind ... CTX for a complicated ... vancomycin to CTX ... Proteins #AMR #PBP #pharmacology
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
Plasmin then acts ... thrornbolytic drugs ... anticoagulant drugs ... #Plasminogen #Pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
allowing it to bind ... allowing it to bind ... by binding to its ... #Pharmacology #Pathophysiology
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
Intraoperative Hypertension ... passing suction catheter ... could have made a drug ... Medical causes: drug ... Anesthesiology #Anesthesia #Intraoperative
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
pancreatitis), Drug ... Tissue penetration (CNS ... to Treatment: Drug ... (ie SJS, DIHS, drug ... Infection: IV catheter
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Intraoperative ... passing suction catheter ... could have made a drug ... Consider known drug ... Anesthesiology #Anesthesia #Intraoperative