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Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... to an allergic reaction ... cell surfaces causes ... an immune reaction ... exposure to allergen causes
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... lgM antibodies bind ... Acute transfusion reaction ... hypersensitivity #reactions
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... : - Drug reaction ... infection - Allergic reaction ... disease Rare causes
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
during an allergic reaction ... Or Inflammatory Reactions ... Chickenpox Other Causes ... Differential #Diagnosis #causes
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... hemolytic transfusion reactions ... Differential #Diagnosis #Causes
Drugs Causing Acute Pancreatitis Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
blisters, possibly crusts ... Bullous impetigo - Reaction ... diabeticorum) - Reaction ... Diagnosis #Algorithm #causes
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics Cellulitis: Deep skin and subcutaneous fat infection Pseudo
Causes of Pseudocellulitis ... avoid allergic reactions ... Inflammatory Causes ... Pseudocellulitis: • Drug reaction ... Neoplastic Causes
Estimated Incidence of Transfusion Reactions Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence. #Diagnosis
of Transfusion Reactions ... of transfusion reactions ... Transfusion #Consent #Reactions
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions
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