51 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Immunosuppressant Drugs ... Immunosuppressant #Drugs ... #Pharmacology #Pathophysiology ... #immunology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... to an allergic reaction ... pollen, foods, drugs ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... and their Actions ... #Pharmacology #Pathophysiology ... #Drugs #Agents
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
When antigens bind ... antibody-mediated immune reaction ... surface - Example: drug ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... allergen (typically a drug ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... Formerly known as drug ... hypersensitivity reaction ... with allergic reaction ... Images #Clinical #Dermatology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... Formerly known as drug ... hypersensitivity reaction ... with allergic reaction ... Images #Clinical #Dermatology
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Groups of Cutaneous Drug ... Reactions IgE-mediated ... reactions: • ... #Cutaneous #Drug ... #Reactions #dermatology
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Injury - Pathophysiology ... Liver #Injury #Pathophysiology ... #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
AIHA, Transfusion reactions ... , Drug-associated ... Membrane Defects, Drugs ... Differential #Diagnosis #hematology