17 results
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... #Diagnosis #autoantibodies ... #signs #symptoms ... #differential #rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... Associated Features: Diagnosis ... #differential #diagnosis ... #comparison #rheumatology ... #table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... lgE antibodies bind ... systemic lupus erythematosus ... Pathophysiology #Allergy #Diagnosis ... #Reactions #Table
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
fever • Delayed-type ... exposure • Diffuse erythematous ... Scarlet #fever #diagnosis ... clinical #photo #signs ... #symptoms
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activity that bind ... Labs/Diagnosis: ... systemic lupus erythematosus ... Cryoglobulins #diagnosis ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... /Symptoms Alopecia ... #SLE #Signs #Symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... Kikuchi disease • Type-I ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Pemphigus Vulgaris vs Bullous Pemphigoid - Comparison Table
Pemphigus Vulgaris
 • Epidemiology: Average age 40-60
 • Time
Pemphigoid - Comparison Table ... , relapsing • Symptoms ... ruptured • Nikolsky sign ... • Antibodies: Autoantibodies ... Pemphigoid #Comparison #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology