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oncology anemia blood myelodysplastic product reactions treatment alopecia antinxp2 antinxp2dm clinical dermatomyositis differential gangrenosum hair hairloss leukostasis loss lysis myelodysplasia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... #MDS #Diagnosis ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Can progress to MDS ... #management #treatment ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS ... Anemia #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... • Anemia • Aplastic ... #diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Alopecia mucinosa, Aplasia ... , Loose anagen syndrome ... Examination: • Signs ... #dermatology #Hairloss
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... due to marrow aplasia ... infographic by Nick Mark MD ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... due to marrow aplasia ... by Nick Mark MD ... #Transfusions #diagnosis ... #management #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Periorbital heliotrope (blue-purple ... chest (in a V-sign ... Muscle atrophy may cause ... #management #rheumatology ... #dermatology
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
progressively worse s/p I&Ds ... Diagnosis? ... Management of PG ... #PG #clinical #photo ... #dermatology #ulcer
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