6 results
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Neonatal Jaundice Causes ... classified as due to (1) ... #Diagnosis #Peds ... #Jaundice #Algorithm ... #Differential #Workup
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Algorithm 1. ... non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #hepatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... typically prolong PT too ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... #differential #diagnosis ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Female:Male 9:1 ... intralobular bile ducts causes ... slightly elevated • Bilirubin ... • AMA titer 1: ... #workup #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL-1 ... thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... 10,000 ng/mL • Hyponatremia ... #Management #Hematology