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diagnosis differential anemia management blood causes product reactions adverseeffects benefits common cvid erythrocytosis fever hcq hemolytic hydroxychloroquine hypogammaglobulinemia immunecompromised immunocompromised
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Hypothyroid • Liver Disease ... MatthewHoMD #Macrocytic ... differential #diagnosis #algorithm ... #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... -100): • Non-hemolytic ... Infections Macrocytic ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... 95 (or 100) is macrocytic ... acute blood loss, hemolysis ... #Diagnosis #Workup ... #Hematology #Microcytic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Vasculitides, IBD, Celiac disease ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... ARUPConsult @ARUPLabs #Hemolytic ... Differential #Diagnosis #Algorithm ... #workup #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Differential Diagnosis Algorithm ... • Burns • Diarrhea ... Cyanotic Heart Disease ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Benefits: ↓ Disease ... intolerance nausea, diarrhea ... Worsening of other diseases ... limited) risk of hemolysis ... #sideeffects #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... • Infectious diarrhea ... Granulomatous disease ... and autoimmune hemolytic ... hypogammaglobulinemia #immunology #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Graft Versus Host Disease ... cutaneous eruptions, diarrhea ... Borrellia (Lyme disease ... Trypanosoma (Chagas disease ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Graft Versus Host Disease ... cutaneous eruptions, diarrhea ... Borrellia (Lyme disease ... Trypanosoma (Chagas disease ... diagnosis #management #hematology
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