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diagnosis differential management blood causes gastroenterology hematology hepatitis product reactions aclf alcoholic chemistry chronic cirrhosis drug druginduced failure idiosyncratic induced
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... disease, Hepatic ... dechallenge • Acute ... disorder (e.g. ascites ... #Algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Liver Injury: ... Liver Injury: ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... Injury (DILI) ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... Unconjugated Bili ... > 90% of Total Bili ... #differential #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Syndrome, Celiac Disease ... #Injury #Differential ... #algorithm #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Differential Diagnosis Algorithm ... • Infiltrative disease ... • Acute liver ... Differential #Diagnosis #Algorithm ... #Hepatology #causes
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
blood, urine and ascites ... kidney injury with ... - Concomitant diseases ... HCV, DILI, HCC, ... #hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... cutaneous eruptions, diarrhea ... , liver abnormalities
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... cutaneous eruptions, diarrhea ... , liver abnormalities
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