9 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... for alternative causes ... Alcohol-related liver disease ... #Diagnosis #Algorithm ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
dose dependent injury ... Idiosyncratic - less common ... symptoms of liver disease ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... • Iatrogenic: DILI ... #diagnosis #algorithm ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Differential #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Cholestatic disease ... • Alcoholic hepatitis ... Bile Ducts • Common ... Others #LFTs #Hepatology ... #Causes
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... • Infectious diarrhea ... and hepatitis ... cancers: Most common ... DDX - Other causes
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
exclude other causes ... - Acute kidney injury ... - Concomitant diseases ... HCV, DILI, HCC, ... #hepatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
(FNHTR): Most common ... Causes purpura & ... More common in women ... Related Acute Lung Injury ... cutaneous eruptions, diarrhea
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
(FNHTR): Most common ... Causes purpura & ... More common in women ... Related Acute Lung Injury ... cutaneous eruptions, diarrhea