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diagnosis liver hematology management lfts transaminitis acute blood cirrhosis mass polycythemia product reactions workup alcoholic alkaline alp biliary chemistry cholangitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic - less common ... symptoms of liver disease ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... for alternative causes ... Alcohol-related liver disease ... #Diagnosis #Algorithm ... #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Wilson disease ... #Differential # ... Hepatology #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... #hepatitis #differential ... #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... Metabolic: Wilson Disease ... • Iatrogenic: DILI ... Diagnosis #causes ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... #Differential # ... #Acute #algorithm ... #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Common Etiologies ... Inflammation - Hepatitis ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... #Diagnosis #Algorithm ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Cholestatic disease ... • Alcoholic hepatitis ... Bile Ducts • Common ... Others #LFTs #Hepatology ... #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... HELLP, Celiac disease ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
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