17 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
lesions • 80% with lung ... splenomegaly Other infections ... multiple lesions Infectious ... Lesions #Brain #differential ... diagnosis #causes #radiology
CNS Ring-Enhancing Lesions - Differential Diagnosis
 • Infections: Cerebral abscess (bacterial, fungal, parasitic), Neurocysticercosis, Tuberculoma, Cerebral
Lesions - Differential ... Diagnosis • Infections ... Malignancy: Metastases (lung ... Demyelinating Disease ... Diagnosis #neurology #radiology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... diarrhea • ... lymphocytic interstitial lung ... and M panel Management ... #diagnosis #management
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Diagnosis Infectious ... : • Rheumatologic ... , Takayasu Disease ... - Metastatic: Lung ... Diagnosis #Causes #cardiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Immunocompromised Host - Differential ... jirovecii • CNS ... • Periodontal Disease ... Bronchitis • Chronic Diarrhea ... Algorithm #Causes #Hematology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Diagnosis Framework Disease ... angioinvasive disease ... Lymphadenopathy, CNS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... rash) • Heart, lung ... SLE], AOSD) • Infection ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... and CNS • Headache ... Erythematosus #Diagnosis #Rheumatology
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
proteinuria • Lungs ... Thyroid (Riedel's), CNS ... Exclusion of Mimics: Infectious ... IGG4 #Diagnosis #Management ... #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... change in the lungs ... Fungal #Diagnosis #Management