10 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
inflammatory disease How ... SLE], AOSD) • Infection ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
activation of macrophages ... Phagocytosis of blood ... : • Infections ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
with excessive macrophage ... can mimic common infections ... Splenomegaly • Low ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Algorithm for the Evaluation of Acute Diarrhea (< 7 days)
Are the following present?
   1.
Algorithm for the ... Ova and parasite ... HIV infection or ... Bloody diarrhea, ... #management #algorithm
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Blood products contain ... Hypothermia: Due to low ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
cutaneous eruptions, diarrhea ... Blood products contain ... Hypothermia: Due to low ... #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... genes and gene products ... Count - Low Hb ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Triggers: ▪ Infections ... : Macrophage Activation ... Low/absent NK-cell ... underlying trigger: Infections ... #Hematology #HemeOnc
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... ABx) → Acute Diarrhea ... (>3 BM/d) ± blood ... Dehydrogenase (↑Sens) - produced ... Fidaxomicin is now
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... • Risk: Can produce ... function of alveolar macrophages ... (It's usually low ... Chest pain, cough, bloody