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diagnosis differential management algorithm causes hodgkins leukemia lymphadenopathy rheumatology acute aki ascites chronic cll common comparison cvid dermatology disorders erythematosus
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... from germinal center ... normal germinal center ... #diagnosis #classification ... #hematology #oncology
Differential Diagnosis for Generalized Lymphadenopathy Viral • HIV • EBV • CMV • HBV • Dengue • Rubella
Malignancy • Lymphoma ... • Metastatic cancer ... Amyloidosis • HLH ... Causes #Algorithm #Oncology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
telomeropathy Cancer ... • Leukemia • Lymphoma ... erythematosus • HLH ... Differential #Diagnosis #Hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
•TB • Lymphoma ... , Breast) • Cancer ... Infection • Cancer ... Algorithm #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... translocation • Types: Classification ... • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
PTLD) Definition: Lymphoid ... for 21% of all cancers ... symptoms, unexplained hematologic ... Diagnosis and classification ... Lymphoproliferative #Disorders #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... B-LNH), solid cancers ... treatment #summary #rheumatology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Patients with Cancer ... Cancer Related ... change disease • Hematologic ... #Oncology #Differential ... #Diagnosis #Classification
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... the non-Hodgkin lymphoma ... Marginal zone lymphoma ... diagnosis #workup #oncology ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Infectious diarrhea ... hepatitis • Lymphoma ... or other cancers ... • Nodules • Lymphoid ... hypogammaglobulinemia #immunology #hematology
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