12 results
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
NG drainage - Diarrhea ... - Polyuria - Hypomagnesemia ... #Potassium #Table ... #Classification ... #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
losses - Chronic diarrhea ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Gl tract loss (Diarrhea ... Diagnosis #Algorithm #causes ... #potassium #low ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Side Effects: Hypomagnesemia ... , diarrhea, nausea ... constipation, diarrhea ... #pharmacology #table
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... Laxative use • Diarrhea ... consumption • Low ... #nephrology #low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
, mild hypomagnesemia ... alkalosis • Normal or low ... (renal potassium ... Congenital chloride diarrhea ... Syndrome #diagnosis #nephrology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... biliary fistula, Diarrhea ... osmotic diuresis, Potassium ... #diagnosis #nephrology ... #magnesium #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... Gitelman syndrome, Hypomagnesemia ... the indicated causes ... of sodium and potassium ... urine #Algorithm #nephrology
Causes of Hypokalemia
I. Decreased intake
   A. Starvation
   B. Clay ingestion
II. Redistribution into
Causes of Hypokalemia ... Gastrointestinal loss (diarrhea ... Differential #Diagnosis #Low ... #Potassium #Classification ... #Causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
only if no clear cause ... Elimination (see Table ... acidosis) • Low ... Management #Treatment #potassium ... #nephrology #K