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diagnosis rheumatology differential classification dermatology management syndrome behcet cryoglobulinemia cryoglobulins dermpath disease lesions manifestations pathology semiology sjogrens skinrash symptoms types
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Differential Diagnosis Algorithm ... insufficiency • Vasculitis ... Mycosis fungoides (cutaneous ... Cryptococcosis #Ulcers #ulcerative ... #causes
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
more): Genital ulceration ... ) • Cutaneous Lesions ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... aphthous ulcers, cutaneous ... purpura: strong sign ... of cutaneous leukocytoclastic ... , and SLE) • Urinalysis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... Henoch-Schönlein purpura) • Cutaneous ... erythematosus (SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... of cutaneous leukocytoclastic ... tract, and often causes ... (lower legs), cutaneous
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... skin (xerosis) • Cutaneous ... vasculitis: 10% ... Nephrogenic DI Hematologic
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