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diagnosis rheumatology differential causes management druginduced erythematosus joint pain systemic approach classification comparison dermatology diffuse dil disease fatigue isolated laboratory
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... Dermatomyositis Erythema chronicum ... IBD • RA • SLE ... lesions • Discoid lupus ... erythematosus • SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... • Evolution: Chronic ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... • Immunologic Workup ... • Evolution: Chronic ... Management #Summary #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... • Systemic Lupus ... • Rheumatoid Arthritis ... Age > 50 • Chronic ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , inflammatory arthritis ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... : • Chronic B-cell
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... • SLE • Polymyalgia ... Differential #Diagnosis #Algorithm
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Differential Diagnosis Algorithm ... Idiopathic - Chronic ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... #Causes #Hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever • Chronic ... spondyloarthropathies, lupus ... hepatitis, herpes • Chronic ... = RA, SLE, psoriatic ... #approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... Screening Tests for Chronic ... #laboratory #workup ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... and often causes arthritis ... inflammation Others: • Lupus ... such as systemic lupus ... vasculitis, and SLE
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